Sex differences in the association between birth weight and adult type 2 diabetes 1 Running title : birth weight and adult type 2 diabetes
نویسندگان
چکیده
3 MRC Integrative Epidemiology Unit, Bristol University, Bristol, U.K. 9 10 E-mail addresses: 11 Esther Zimmermann: [email protected] 12 Michael Gamborg: [email protected] 13 Thorkild I. A. Sørensen: [email protected] 14 Jennifer L. Baker: [email protected] 15 16 Corresponding author: 17 Esther Zimmermann, Institute of Preventive Medicine, Frederiksberg Hospital, Nordre Fasanvej 57, 18 Hovedvejen, Indgang 5, stuen, 2000 Frederiksberg, Denmark. 19 Email: [email protected], phone +45 3816 3051, fax +45 3816 3119 20
منابع مشابه
Sex Differences in the Association Between Birth Weight and Adult Type 2 Diabetes.
Low birth weight is a well-established risk factor for type 2 diabetes, but the risk at high birth weight levels remains uncertain. Potential sex differences in the associations are unexplored. We investigated whether sex influences the association of birth weight and adult type 2 diabetes, using a cohort of 113,801 men and 109,298 women, born 1936-1983, from the Copenhagen School Health Record...
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BACKGROUND A feature of the Asian Indian phenotype is low birth weight with increased adult type 2 diabetes risk. Most populations show consistent associations between low birth weight and adult type 2 diabetes. Recently, two birth weight-lowering loci on chromosome 3 (near CCNL1 and ADCY5) were identified in a genome-wide association study, the latter of which is also a type 2 diabetes locus. ...
متن کاملSize at birth and glucose intolerance in a relatively genetically homogeneous, high-birth weight population.
BACKGROUND The results of epidemiologic studies have linked birth size to adult glucose intolerance. OBJECTIVE We investigated this association in a genetically homogeneous population with higher birth weights and a lower prevalence of type 2 diabetes than previously studied. DESIGN The subjects were 2362 men and 2286 women aged 33-65 y. Size at birth was obtained from the National Archives...
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OBJECTIVE small size at birth has been associated with increased risk of type 2 diabetes. Our aim was to evaluate how risk of diabetes associated with low birth weight is affected by accumulation of body mass from childhood to adulthood. RESEARCH DESIGN AND METHODS Subjects from the 1958 British birth cohort (born 3-9 March 1958) have been followed regularly since birth. In the survey at 41 y...
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